However, this observation did not reach incorporation into daily clinical practice or the respective guidelines. Several studies report increased levels of HbA1c in nondiabetic elderly. If you have a hemoglobin variant, your test may need to be sent to a specialized lab or you may need a different test for diagnosis and monitoring of diabetes.Measurement of gylcated hemoglobin A1c (HbA1c) plays a central role in monitoring quality of antidiabetic therapy and in the diagnosis of diabetes. Hemoglobin variants are more common among people of African, Mediterranean or Southeast Asian descent. The presence of other variants of the protein may result in inaccurate A1C test results. The most common form of the oxygen-transporting hemoglobin protein is called hemoglobin A.
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